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Category: EnzymesarrowSynthases/SynthetasesarrowNO SynthasesarrowNon-Selective NOS
Cat.No. Product Name
0771 L-NMMA acetate  
Price and Availability

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L-NMMA
Chemical Name: NG-Monomethyl-L-arginine acetate

Biological Activity:

Competitive, irreversible inhibitor of all three NOS isoforms.

Technical Data:

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M.Wt: 248.28
Formula: C7H16N4O2.CH3CO2H
Storage: Store at RT
Solubility: Soluble to 50 mM in Water
CAS No: [53308-83-1]

Resources:

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    References:

    Saksuma et al (1988) Identification of arginine as a precursor of endothelium-derived relaxing factor. Proc.Natl.Acad.Sci.USA 85 8664. Rees et al (1990) Characterisation of three inhibitors of endothelial nitric oxide synthase in vivo and in vitro. Br.J.Pharmacol. 101 746. Olken et al (1991) Inactivation of macrophage nitric oxide synthase activity by N(G)-methyl-L-arginine. Biochem.Biophys.Res.Comm. 177 828. Reif and McCreedy et al (1995) N-nitro-L-arginine and N-monomethyl-L-arginine exhibit a differential pattern of inactivation toward the three nitric oxide synthases. Arch.Biochem.Biophys. 320 170.
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    Keywords: L-NMMA, Synthases / Synthetases, Non-selective NOS Inhibitor, LNMMA, Tocris Bioscience

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    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
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