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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGABAA and GABAC ReceptorsarrowMiscellaneous GABA
Cat.No. Product Name
0780 NCS-382  
Price and Availability

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NCS-382
Chemical Name: 6,7,8,9-Tetrahydro-5-hydroxy-5H-benzocyclohept-6-yliden eacetic acid

Biological Activity:

γ-Hydroxybutyric acid antagonist, anticonvulsant.

Technical Data:

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M.Wt: 218.25
Formula: C13H14O3
Storage: Desiccate at +4°C
Solubility: Soluble to 100 mM in DMSO
Purity: >99%
CAS No: [131733-92-1]

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    References:

    Maitre et al (1990) A specific γ-hydroxybutyrate receptor ligand possesses both antagonist and anticonvulsant properties. J.Pharmacol.Exp.Ther. 255 657. Schmidt et al (1991) Anti-sedative and anti-cataleptic properties of NCS-382, a γ-hydroxybutyrate receptor antagonist. Eur.J.Pharmacol. 203 393. King et al (1997) Gammahydroxybutyrate (GHB) receptor ligand effects on evoked synaptic field potentials in CA1 of the rat hippocampal slice. J.Neural Transm. 104 1177.
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    Keywords: NCS-382, Ligand-gated Ion Channels, Antagonist Of G Hydroxybutyric Acid, NCS382, Tocris Bioscience
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