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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGABAA and GABAC ReceptorsarrowGABAA ReceptorsarrowAgonists
Cat.No. Product Name
0289

Muscimol  

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Muscimol
Chemical Name: 5-Aminomethyl-3-hydroxyisoxazole

Biological Activity:

Potent GABAA receptor agonist and partial GABAC receptor agonist.

Technical Data:

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M.Wt: 114.1
Formula: C4H6N2O2
Storage: Store at RT
Solubility: Soluble to 100 mM in 1eq. NaOH and to 100 mM in Water
Purity: >98%
CAS No: [2763-96-4]

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    References:

    Johnston et al (1968) Central actions of ibotenic acid and muscimol. Biochem.Pharmacol. 17 2488. Akhondzadeh and Stone (1995) Induction of a novel form of hippocampal long-term depression by muscimol: involvement of GABAA but not glutamate receptors. Br.J.Pharmacol. 115 527. Johnstone (1996) GABAC receptors: relatively simple transmitter-gated ion channels? TiPS 17 319.

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    Keywords: Muscimol, Ligand-gated Ion Channels, Potent GABAA Agonist, Tocris Bioscience
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    GABA Receptors
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