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Category: Ion ChannelsarrowPotassium ChannelsarrowATP-Activated Potassium Channels
Cat.No. Product Name
0583 Minoxidil  
Price and Availability

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Minoxidil
Chemical Name: 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide

Biological Activity:

Antihypertensive. Antialopecia agent. K+ channel (KATP) activator.

Technical Data:

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M.Wt: 209.25
Formula: C9H15N5O
Storage: Store at RT
Solubility: Soluble to 25 mM in Ethanol and to 25 mM in DMSO
CAS No: [38304-91-5]

Resources:

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    References:

    Merck index 12  6290. Meisheri et al (1993) Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil. Biochem.Pharmacol. 45 271. Tsoporis et al (1993) Effects of the arterial vasodilator minoxidil on cardiovascular structure and sympathetic activity in spontaneously hypertensive rats. J.Hypertens. 11 1337. Lachgar et al (1998) Minoxidil upregulates the expression of vascular endothelial growth factor in human hair dermal papilla cells. Br.J.Dermatol. 138 407.
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    Keywords: Minoxidil, Potassium Channels, K+ Channel (KATP) Opener, Tocris Bioscience

    Literature in this Area
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    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
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