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Category:
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Cellular Processes and Components Signal TransductionG Protein (Heterotrimeric)
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Biological Activity:
Amphiphilic
G protein activator peptide that binds to Gi and Go. Also
binds with high affinity to calmodulin (Kd ~ 0.9 nM) and inhibits
sarcoplasmic reticulum Ca2+-ATPase (Ki = 4.4 μM).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Higashijima et al (1990) Regulation of Gi
and Go by mastoparan, related amphiphilic peptides, and hydrophobic
amines. J.Biol.Chem. 265 14176. Sukumar and Higashijima
(1992) G protein-bound conformation of mastoparan-X, a receptor-mimetic
peptide. J.Biol.Chem. 267 21421. Longland et al
(1999) The mechanism of inhibition of the Ca2+-ATPase by mastoparan.
J.Biol.Chem. 274 14799.
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or by Research Area
Keywords: Mastoparan X, Signal Transduction, G Protein Activator Peptide, Tocris Bioscience
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