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Category: EnzymesarrowPhosphodiesterases
Cat.No. Product Name
0432 MY-5445  
Price and Availability

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MY-5445
Chemical Name: 1-(3-Chlorophenylamino)-4-phenylphthalazine

Biological Activity:

Specific inhibitor of cyclic GMP phosphodiesterase, selective for PDE5 (IC50 = 0.5 μM).

Technical Data:

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M.Wt: 331.8
Formula: C20H14ClN3
Storage: Store at RT
Solubility: Soluble to 50 mM in DMSO and to 5 mM in Ethanol
CAS No: [78351-75-4]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
    Product/Material Safety Data Sheet: View current batch

    References:

    Hagiwara et al (1984) Effect of 1-(3-chloroanilino)-4-phenylphthalazine (MY-5445), a specific inhibitor of cyclic GMP phosphodiesterase, on human platelet aggregation. J.Pharmacol.Exp.Ther. 228 467. Hidaka and Endo et al (1984) Selective inhibitors of three forms of cyclic nucleotide phosphodiesterase, basic and potential clinical applications. Adv.Cyclic Nucleotide Protein Phosphor.Res. 16 245.
    View related products by Pharmacological Action or by Research Area

    Keywords: MY-5445, Phosphodiesterases, PDE5 Inhibitor, MY5445, Tocris Bioscience

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