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Category:
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7TM Receptors Adenosine ReceptorsAntagonists
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Cat.No.
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Product Name
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2403 |
MRS 3777 hemioxalate
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Price and Availability
Click here for full price details of
MRS 3777
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Chemical Name:
2-Phenoxy-6-(cyclohexylamino)purine hemioxalate |
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Biological Activity:
High affinity adenosine A3 receptor
antagonist (Ki = 47 nM) that displays > 200-fold selectivity
versus A1, A2A and A2B receptors.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Perreira et al (2005)
"Reversine" and its 2-substituted adenine derivatives as potent and
selective A3 adenosine receptor antagonists. J.Med.Chem. 48
4910. Jacobson and Gao (2006) Adenosine receptors as therapeutic
targets. Nat.Rev.Drug Discov. 5 247. Moro et al (2006)
Progress in the pursuit of therapeutic adenosine receptor antagonists.
Med.Res.Rev. 26 131.
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or by Research Area
Keywords: MRS 3777, Adenosine Receptors, High Affinity, Selective A3 Antagonist, MRS3777, Tocris Bioscience
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| “I am grateful for your honesty and courtesy. The principles of Tocris are very different to that of your competitors who, in fact, have put our inhibitor on the market without any approval, exhibiting a pirate policy and a total absence of ethics..” Researcher, University of Pisa, Italy |
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