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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowP2X ReceptorsarrowOther P2X
Cat.No. Product Name
1203 MRS 2219
Price and Availability

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MRS 2219
Chemical Name: 1,5-Dihydro-3-hydroxy-8-methyl[1,3,2]dioxaphosphepino[5 ,6-c]pyridin-9-ol-3-oxide

Biological Activity:

A selective potentiator of ATP-evoked responses at rat P2X1 receptors (EC50 = 5.9 μM).

Technical Data:

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M.Wt: 231.14
Formula: C8H10NO5P
Storage: Desiccate at +4°C
Solubility: Soluble to 100 mM in 1eq. NaOH
Purity: >99%
CAS No: [14141-47-0]

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    References:

    Jacobson et al (1998) A pyridoxine cyclic phosphate and its 6-axoaryl derivative selectively potentiate and antagonise activation of P2X1 receptors. J.Med.Chem. 41 2201.
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    Keywords: MRS 2219, Ligand-gated Ion Channels, Potentiates P2X1-mediated Responses, MRS2219, Tocris Bioscience
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