ML 9 Hydrochloride | Kinases | Myosin Light Chain Kinase Inhibitor | ML9 Hydrochloride

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Cat.No.	Product Name
0431	ML 9 hydrochloride

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ML 9 hydrochloride

Chemical Name: 1-(5-Chloronaphthalenesulfonyl)homopiperazine hydrochloride

Biological Activity:

Selective inhibitor of myosin light chain kinase (MLCK). K_i values are 32, 4, and 54 μM for PKA, MLCK, and PKC respectively.

Technical Data:

M.Wt:	361.29
Formula:	C₁₅H₁₇ClN₂O₂S.HCl
Storage:	Desiccate at RT
Solubility:	Soluble to 25 mM in DMSO
Purity:	>99%
CAS No:	[105637-50-1]

Resources:

Certificate of Analysis / MSDS:

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References:

Hidaka and Hagiwara (1987) Pharmacology of the isoquinoline sulfonamide protein kinase C inhibitors. TiPS 8 162. Seto et al (1991) Effects of HA1077, a protein kinase inhibitor, on myosin phosphorylation and tension in smooth muscle. Eur.J.Pharmacol. 195 267. Hidaka and Koybashi (1992) Pharmacology of protein kinase inhibitors. Ann.Rev.Pharmacol.Toxicol. 32 377.

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Keywords: ML 9 Hydrochloride, Kinases, Myosin Light Chain Kinase Inhibitor, ML9 Hydrochloride, Tocris Bioscience

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