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Category:
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7TM Receptors 5-HT Receptors5-HT1 Receptors5-HT1A
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Cat.No.
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Product Name
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0412 |
MDL 72832 hydrochloride
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Price and Availability
Click here for full price details of
MDL 72832 hydrochloride
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Chemical Name:
8-[4-(1,4-Benzodioxan-2-ylmethylamino)butyl]-8-azaspiro
[4.5]decane-7,9-dione hydrochloride |
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Biological Activity:
A potent ligand at 5-HT1A
receptors, with mixed agonist and antagonist properties. An agonist at
post-synaptic 5-HT1A receptors.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Mir et al (1988) MDL 72832: a potent and stereoselective ligand at central
and peripheral 5-HT1A receptors. Eur.J.Pharmacol. 149
107. Millan et al (1993) Induction of hypothermia as a model of
5-hydroxytryptamine1A receptor-mediated activity in the rat - a
pharmacological characterization of the actions of novel agonists and
antagonists. J.Pharmacol.Exp.Ther. 264 1364.
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or by Research Area
Keywords: MDL 72832 Hydrochloride, 5-HT Receptors, Potent 5-HT1A Ligand, MDL72832 Hydrochloride, Tocris Bioscience
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