(S)-MCPG | Glutamate (Metabotropic) Receptors | Active Isomer Of Cat. No. 0336 | MCPG

Category:

Cat.No.	Product Name
0337	(S)-MCPG

Price and Availability

Click here for full price details of
(S)-MCPG

Chemical Name: (S)-a-Methyl-4-carboxyphenylglycine

Biological Activity:

Active isomer of (RS)-MCPG (Cat. No. 0336). Non-selective group I/group II metabotropic glutamate receptor antagonist.

Technical Data:

M.Wt:	209.2
Formula:	C₁₀H₁₁NO₄
Storage:	Store at RT
Solubility:	Soluble to 10 mM in Water and to 100 mM in 1.1eq. NaOH
Purity:	>99%
CAS No:	[150145-89-4]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

For specific/earlier batch please select:

Product/Material Safety Data Sheet: View current batch

For specific/earlier batch please select:

References:

Jane et al (1993) Stereospecific antagonism by (+)-α-methyl-4-carboxyphenylglycine (MCPG) of 1S,3R-ACPD induced effects in neonatal rat motoneurones and rat thalamic neurones. Neuropharmacology 32 725. Collingridge and Watkins (1994) Phenylglycine derivatives as metabotropic glutamate receptor antagonists. TiPS 15 333. Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br. J. Pharmacol. 117 1493. Bordi et al (1996) Effects of the metabotropic glutamate receptor antagonist MCPG on spatial and context-specific learning. Neuropharmacology 35 1557

View related products by Pharmacological Action or by Research Area

Keywords: (S)-MCPG, Glutamate (Metabotropic) Receptors, Active Isomer Of Cat. No. 0336, MCPG, Tocris Bioscience

Literature in this Area

Scientific Reviews

Metabotropic Glutamate Receptors
Request Copy | Download PDF

The Ins & outs of Glutamate Transporter Pharmacology
Request Copy | Download PDF

Featured New Product

GluR1/2 selective AMPA antagonist

2770 Philanthotoxin 74

Subtype-selective AMPA receptor antagonist; inhibits GluR1/2 but not GluR2/3 receptors.

View all Featured New Products

New Products in this Area

	2963	MMPIP hydrochloride
	Potent, allosteric mGlu₇-selective antagonist
	2921	MTEP
	Potent, selective mGlu₅ antagonist
	2453	LY 379268
	Highly selective group II mGlu agonist
	2031	Anti-mGlu₇
	Antibody recognising human mGlu₇ receptors
	2032	Anti-mGlu₅
	Antibody recognising rat mGlu₅ receptors
	2029	Anti-mGlu_2/3
	Antibody recognising human mGlu₂ and mGlu₃ receptors
	2027	Anti-mGlu₂
	Antibody recognising rat mGlu₂ receptors

for new product e-alerts

User ID
Password