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Category: 7TM ReceptorsarrowPeptides (Hypothalamic/Pituitary Hormones)arrowGonadotropin-releasing Hormone Receptors
Cat.No. Product Name
2873 Leuprolide
Alternative name(s): Leuoprorelin
Price and Availability

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Leuprolide

Biological Activity:

Gonadotropin-releasing hormone (GnRH, luteinising hormone-releasing hormone, LHRH) receptor agonist. Suppresses estradiol, LH and FSH serum levels and represses the growth of experimental rat endometriosis.

Technical Data:

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M.Wt: 1209.41
Formula: C59H84N16O12
Storage: Desiccate at -20°C
CAS No: [74381-53-6]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
    Product/Material Safety Data Sheet: View current batch

    References:

    Okada et al (1988) One-month release injectable microcapsules of a luteinizing hormone-releasing hormone agonist (leuprolide acetate) for treating experimental endometriosis in rats. J.Pharmacol.Exp.Ther. 244 744. Salvador et al (2001) Effects of the luteinising hormone-releasing hormone (LH-RH) agonist leuprolide on adenylyl cyclase regulation through G-protein coupled receptors in rat ventral prostate. Eur.J.Pharmacol. 37 641. Uday et al (2007) LHRH antagonist attenuates the effect of fluoxetine on marble-burying behavior in mice. Eur.J.Pharmacol. 563 155.
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    Keywords: Leuprolide, Peptides (Hypothalamic / Pituitary Hormones), GnRH (LHRH) Receptor Agonist, Leuoprorelin, Tocris Bioscience

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