Tocris Bioscience
 Welcome to Tocris

Home Products Technical Support Customer Support Literature Custom Synthesis
Category: 7TM ReceptorsarrowPeptides (Gastrointestinal)arrowCCK Receptors
Cat.No. Product Name
1018 LY 225910
Price and Availability

Click here for full price details of
LY 225910

Other Information:

Sold with the permission of Eli Lilly and Company
Chemical Name: 2-[2-(5-Bromo-1H-indol-3-yl)ethyl]-3-[3-(1-methylethoxy )phenyl]-4-(3H)-quinazoline

Biological Activity:

Potent CCK2 receptor antagonist (IC50 = 9.3 nM  for inhibition of 125I-labelled CCK-8 sulphate binding at mouse brain membranes).

Technical Data:

 Click here for more information on batch specific data
M.Wt: 502.41
Formula: C27H24BrN3O2
Storage: Desiccate at -20°C
Solubility: Soluble to 100 mM in DMSO
CAS No: [133040-77-4]

Resources:

    		•

    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    For specific/earlier batch please select:  
    Product/Material Safety Data Sheet: View current batch
    For specific/earlier batch please select:  

    References:

    Yu et al (1991) Quinazolinone cholecystokinin receptor ligands. J.Med.Chem. 34 1505. Suman-Chauhan et al (1996) The influence of guanyl nucleotide on agonist and antagonist affinity at guinea-pig CCK-B / gastrin receptors: binding studies using [3H]PD140376. Regul.Peptides 65 37.
    View related products by Pharmacological Action or by Research Area

    Keywords: LY 225910, Peptides (Gastrointestinal), Potent CCK2 Antagonist, LY225910, Tocris Bioscience
    New Product Guide
    Tocris Bioscience. Our latest New Product Guide highlights over 140 new productsOur latest New Product Guide highlights over 140 new products.
    Request Copy / View PDF
    First-Class Technical Expertise
    At Tocris we understand that planning an experiment is complicated and that it is important to be able to interact with knowledgeable people who care about helping you find the products and information you need.

    Our specialist scientists provide the highest level of service for every enquiry, fully researching each one and supplying the most accurate response, quickly.

    We encourage our customers to contact us; no question is too small or insignificant.
    New Products in this Area

     3007Apelin-17 (human, bovine)
     Endogenous APJ receptor agonist
     3008Galanin (porcine)
     Galanin receptor agonist
     2951[Des-octanoyl]-Ghrelin (rat)
     Major circulating form of ghrelin; devoid of activity at GHS receptor
     3006Gastrin I (human)
     Selective CCK2 agonist
     2607CI 988
     Potent and selective CCK2 antagonist
     2608PD 135158
     Potent and selective CCK2 antagonist
     2711Bay 55-9837
     Potent and selective VPAC2 agonist
     2699AR-M 1896
     Selective GalR2 agonist
     1524LY 288513
     Selective CCK2 antagonist
     2698M871
     Selective GalR2 antagonist
     2697M617
     Selective GalR1 agonist
     2696Galanin (1-29) (rat, mouse)
     Non-selective galanin receptor agonist
     2190SR 27897
     Potent and selective CCK1 antagonist
     2261L-692,585
     Potent, non-peptide GHS receptor agonist
    Sign-up for new product e-alerts
    Log In / Register

    User ID
    Password
    If you are not registered with us Create Account
    Home | About | Contact | Environment | Distributors | Glossary | Ordering | Security | Privacy | Terms & Conditions | Services | Site Map