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Category: 7TM Receptorsarrow5-HT Receptorsarrow5-HT1 Receptorsarrow5-HT1A
Cat.No. Product Name
1869 Ipsapirone
Alternative name(s): TVX Q 7821
Price and Availability

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Ipsapirone
Chemical Name: 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzis othiazol-3(2H)-one-1,1-dioxide

Biological Activity:

Selective 5-HT1A receptor agonist (Ki = 10 nM). Anxiolytic in vivo.

Technical Data:

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M.Wt: 401.48
Formula: C19H23N5O3S
Storage: Store at RT
Solubility: Soluble to 10 mM in DMSO
Purity: >99%
CAS No: [95847-70-4]

Resources:

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    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Traber et al (1984) Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821. Brain Res.Bull. 12 741. Glaser and Traber (1985) Binding of the putative anxiolytic TVX Q 7821 to hippocampal 5-hydroxytryptamine (5-HT) recognition sites. Naunyn-Schmied.Arch.Pharmacol. 329 211. Maj et al (1987) Central action of ipsapirone, a new anxiolytic drug, on serotoninergic, noradrenergic and dopaminergic functions. J.Neural.Transm. 70 1.
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    Keywords: Ipsapirone, 5-HT Receptors, Selective 5-HT1A Agonist, TVX Q 7821, Tocris Bioscience
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