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Category:
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Cellular Processes and Components Signal TransductionCalcium SignallingGeneral Calcium Signalling Agents
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Cat.No.
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Product Name
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2092 |
Ionomycin free acid
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Price and Availability
Click here for full price details of
Ionomycin free acid
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Chemical Name:
(4R,6S,8S,10Z,12R,14R,16E,18R,19R,20S,21S)-11,19,21-Tri
hydroxy-4,6,8,12,14,18,20-heptamethyl-22-[(2S,2'R,5S,5'
S)-octahydro-5'-[(1R)-1-hydroxyethyl]-2,5'-dimethyl[2,2
'-bifuran]-5-yl]-9-oxo-10,16-docosadienoic acid |
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Biological Activity:
Calcium
ionophore; more specific than A23187 (Cat. No. 1234).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Liu and
Hermann (1978)
Characterization of ionomycin as a calcium ionophore. J.Biol.Chem. 253 5892.
Kaufmann et al (1980) Cation transport and specificity of
ionomycin. Comparison with ionophore A23187 in rat liver mitochondria.
J.Biol.Chem. 255 2735. Elzi et al (2001) Ionomycin
causes activation of p38 and p42/44 mitogen-activated protein kinases in human
neutrophils. Am.J.Physiol.Cell Physiol. 281 C350.
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View related products by Pharmacological Action
or by Research Area
Keywords: Ionomycin Free Acid, Signal Transduction, Calcium Ionophore, Tocris Bioscience
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Literature in this Area Scientific Reviews
Mechanisms for Manipulating Intracellular Calcium Buffering Download PDF Cancer Research Guide | Our unique collection of more than 300 products related to cancer research, including the very latest exclusive research tools. | | Request Copy / View PDF |
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