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Category: Cellular Processes and ComponentsarrowSignal TransductionarrowInositol and cAMP SignallingarrowInositol Lipids
Cat.No. Product Name
1482 D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt
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D-myo-Inositol 1,4,5-trisphosphate, hexapotassium salt

Biological Activity:

Important second messenger involved in Ca2+ mobilisation from intracellular stores (EC50 = 0.1 μM). Formed from the enzymatic hydrolysis of phosphatidyl inositol-4,5-bisphosphate.

Technical Data:

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M.Wt: 648.64
Formula: C6H9O15P3.K6
Storage: Desiccate at -20°C
Solubility: Soluble in Water
CAS No: [103476-24-0]

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    References:

    Joseph et al (1984) myo-Inositol 1,4,5-trisphosphate. J.Biol.Chem. 259 3077. Murphy et al (1996) Enantiomers of myo-inositol-1,3,4-trisphosphate and myo-inositol-1,4,6-trisphosphate: stereospecific recognition by cerebellar and platelet myo-inositol-1,4,5-trisphosphate receptors. Mol.Pharmacol. 50 1223. Wilcox et al (1998) New developments in the molecular pharmacology of the myo-inositol 1,4,5-trisphosphate receptor. TiPS 19 467.
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    Keywords: D-myo-Inositol 1,4,5-trisphosphate, Hexapotassium Salt, Signal Transduction, Ca2+ Mobilising Second Messenger, Dmyo-Inositol 1,4,5-trisphosphate, Hexapotassium Salt, Tocris Bioscience
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