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"images" has 128 results in Products.

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ER-LIVE™ Endoplasmic Reticulum Dye

Cat. No. 9010/50UL
Description: Ready-to-use fluorescent probe for long term imaging of ER in live cells, can be multiplexed with ChromaLIVE Deep Red for phenotypic screening
Purity: ≥90% (HPLC)
Pricing & Availability Qty

SiRA 2

Cat. No. 7544/2
Description: Fluorogen for SiRA light-up aptamer. Application: confocal microscopy, SRM (including STED)
Purity: ≥90% (HPLC)
Pricing & Availability Qty

DMHBO+

Cat. No. 7764/10
Description: Fluorescent upon binding to Chili aptamer; for imaging RNA in cells
Purity: ≥98% (HPLC)
Pricing & Availability Qty

NucleoLIVE™ Blue Non-Toxic Dye

Cat. No. 9011/50UL
Description: Ready-to-use fluorescent probe for long term high content nuclear imaging in live cells
Purity: ≥90% (HPLC)
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ChromaLIVE™ Deep Red Non-Toxic Dye

Cat. No. 9009/10UL
Description: Ready-to-use fluorescent probe for long term high content phenotypic screening of live cells, can be multiplexed with NucleoLIVE
Purity: ≥90% (HPLC)
Pricing & Availability Qty

Rhobo6 ECM Dye

Cat. No. 8876/76U
Description: Fluorogenic probe for labeling the extracellular matrix (ECM) in live tissues
Purity: ≥85% (HPLC)
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ChromaLIVE™ Non-Toxic Dye

Cat. No. 8934/10UL
Description: Ready-to-use fluorescent probe for long term high content phenotypic screening of live cells
Purity: ≥90% (HPLC)
Pricing & Availability Qty

SALAD1

Cat. No. 8974/500U
Description: Ultrabright fluorogenic dye for imaging RNA in living cells; activated by binding Mango aptamers
Purity: ≥95% (HPLC)
Pricing & Availability Qty

DFHBI 1T

Cat. No. 5610/10
Description: GFP fluorophore mimic for imaging RNA in living cells; activated by binding Spinach2 and Broccoli aptamers
Purity: ≥98% (HPLC)
Pricing & Availability Qty

DFHBI

Cat. No. 5609/10
Description: GFP fluorophore mimic for imaging RNA in living cells; activated by binding Spinach2 and Broccoli aptamers
Purity: ≥98% (HPLC)
Pricing & Availability Qty
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"images" has 17 results in Targets.

Aptamer-based RNA Imaging

Light-up RNA aptamers or Fluorescent light-up aptamers (FLAPs) are a genetically-encoded RNA imaging platform. They are designed to bind specific fluorogenic dyes that 'light-up' only in the bound state. This property of 'fluorogenicity' means that fluorescence can be 'switched on' upon RNA expression. Light-up aptamers can be thought of as the RNA counterpart to fluorescent proteins, such as GFP. Commonly used light-up aptamers include Spinach, Mango, Corn and Broccoli, named for their vibrant colors.

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Bioluminescent Substrates

Bioluminescent substrates are commonly utilized for non-invasive monitoring of biological processes, for example in bioluminescence imaging (BLI) in both in vivo and in vitro settings. Luciferase substrates emit light when they become oxidized, which can be detected using fluorescence microscopy.

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BromoCatch Platform

BromoCatch is a new, versatile self-labelling protein (SLP) tag platform for efficient protein analysis and live cell imaging.

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Caged Compounds

Photolysis is an experimental tool that enables the release of ligands adjacent to their receptors, overcoming the effects of diffusion that will otherwise dominate the kinetics of the receptor activation. It requires photolabile precursors of relevant ligands, known as caged compounds.

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Fluorescence Imaging

Tocris offers a broad range of fluorescent and bioluminescent reagents, to facilitate the visualization of sub-cellular components in live and fixed cells with high sensitivity and selectivity. The product range includes fluorescent probes, dyes and indicators.

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Fluorescent Probes for Imaging Bacteria

Fluorescent probes for imaging bacteria are useful for advancing bacterial research and antibiotic design. One technique for studying bacteria, is to incorporate fluorescent probes such as Fluorescent D-amino acids (FDAAs) into the cell wall of live bacteria. FDAAs are suitable for use with confocal and super-resolution microscopy (SRM).

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Haloalkane Janelia Fluor® Dyes

The Janelia Fluor® Haloalkane dyes are cell-permeable fluorogenic dyes with a chloroalkane handle. They covalently bind to HaloTag® self-labeling protein which can be used for tagging a protein of interest. Several of these dyes show a high degree of fluorogenicity following binding to the HaloTag protein, enabling wash-free imaging. They are suitable for use in live-cells, tissues and in vivo imaging, and are especially well suited to super-resolution microscopy (SRM) techniques.

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Imaging Applications

Tocris offers an extensive range of fluorescent and bioluminescent dyes, probes, indicators, buffers and more to support all your fluorescent imaging needs. We have grouped all the main dyes, counter stains and buffers according to applications below. You will also find links to the comprehensive range of antibodies from our sister brands R&D Systems™ and Novus Biologicals, including over 40,000 IHC validated antibodies.

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Live-cell Imaging

Live-cell imaging gives insights into cellular processes in real-time and can be used to monitor the effects of various stimuli or treatments on cell behavior, providing valuable information for drug discovery and biology research.

Tocris offers fluorescent reagents to observe dynamic cellular processes in living cells over time with high sensitivity and selectivity.

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"images" has 2 results in Resources.

Fluorescent Dyes and Probes Product Guide

This product guide provides a background to the use of Fluorescent Dyes and Probes, as well as a comprehensive list of our:

  • Fluorescent Dyes, including Janelia Fluor® Dyes
  • Fluorescent Probes for Advanced Microscopy and Live Cell Imaging
  • Fluorescent Probes to Support In Vivo, Deep Tissue, and Bioluminescence Imaging
  • Fluorescent Probes and Reagents for Organoids and 3D Cell Culture Imaging
  • Aptamer-based RNA Imaging Reagents
  • Fluorescent Probes for Imaging Bacteria
  • ClariTSATM Fluorophore Kits
  • TSA Reagents for Enhancing IHC, ICC & FISH Signals
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Novel Live-cell and Fixable Mitochondrial Probes

Fluorescent probes that accumulate in the mitochondria are useful tools to explore mitochondrial function and cell health. This poster reports the development inhouse and characterization of novel fluorescent probes, known as MitoBrilliant that specifically localize to mitochondria due to mitochondrial membrane potential. The probes are suitable for live or fixed cell staining. The data demonstrate the specificity and enhanced properties of our MitoBrilliant dyes and their use in a range of applications. This poster was presented at CYTO 2022, June 2022, Philadelphia, USA.

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