Tocris Bioscience
 Welcome to Tocris

| Advanced Search
Home Products Technical Support Customer Support Literature Custom Synthesis
Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNMDA SelectivearrowNMDA SitearrowAgonists
Cat.No. Product Name
0285 Ibotenic acid  
Price and Availability

Click here for full price details of
Ibotenic acid
Chemical Name: a-Amino-(3-hydroxy-5-isoxazolyl)acetic acid

Biological Activity:

NMDA and metabotropic glutamate receptor agonist.

Technical Data:

 Click here for more information on batch specific data
M.Wt: 158.11
Formula: C5H6N2O4
Storage: Desiccate at -20°C
Solubility: Soluble to 10 mM in Water
Purity: >98%
CAS No: [2552-55-8]

Resources:

    		•

    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    For specific/earlier batch please select:  
    Product/Material Safety Data Sheet: View current batch
    For specific/earlier batch please select:  

    References:

    Johnston et al (1968) Central actions of ibotenic acid and muscimol. Biochem.Pharmacol. 17 2488. Watkins and Evans (1981) Excitatory amino acid transmitters. Ann.Rev.Pharmacol.Toxicol. 21 165. Nakanishi (1992) Molecular diversity of glutamate receptors and implications for brain functions. Science 258 597. Pin and Duvoisin (1995) The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34 1.
    View related products by Pharmacological Action or by Research Area

    Keywords: Ibotenic Acid, Ligand-gated Ion Channels, Non-selective NMDA Agonist, Tocris Bioscience
    Literature in this Area
    Scientific Reviews
    The Ins & outs of Glutamate Transporter Pharmacology
    Download PDF
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
    Featured New Product
    GluR1/2 selective AMPA antagonist
    2770   Philanthotoxin 74
    Subtype-selective AMPA receptor antagonist; inhibits GluR1/2 but not GluR2/3 receptors.
    View all Featured New Products
    New Products in this Area

     2905TB 21007
     α5-selective GABAA inverse agonist
     2738Org 20599
     Positive allosteric modulator and direct agonist of GABAA receptors
     2805Diazepam
     Benzodiazepine agonist
     2832Midazolam hydrochloride
     Benzodiazepine agonist
     2972A 438079 hydrochloride
     Competitve P2X7 antagonist
     2736Sazetidine A dihydrochloride
     Subtype-selective α4β2 receptor desensitiser
     2929PEPA
     Allosteric potentiator of AMPA receptor desensitisation
     2973Piracetam
     Nootropic; modulates Na+-flux at AMPA receptors
     2734U 89843A
     Positive allosteric modulator of GABAA
     2903Granisetron hydrochloride
     5-HT3 antagonist
     2782TCS 46b
     Orally active, subtype-selective NR1A/NR2B antagonist
     2931Spinorphin
     Potent P2X3 antagonist
     2851Nefiracetam
     Cognitive enhancer
     2770Philanthotoxin 74
     GluR1/2 selective AMPA antagonist
     2891Ondansetron hydrochloride
     Selective 5-HT3 antagonist
     2820(+)-Tubocurarine chloride
     Nicotinic receptor antagonist
     2843Mecamylamine hydrochloride
     Non-competitive nicotinic receptor antagonist
     2810Carbamoylcholine chloride
     Cholinergic receptor agonist
     1521LY 233053
     Competitive NMDA receptor antagonist
     2745U 93631
     GABAA receptor antagonist
     2785Strychnine hydrochloride
     Competitive glycine receptor antagonist
     2737TC 2559 difumarate
     Selective partial agonist at α4β2 receptors
     2809Acetylcholine chloride
     Endogenous neurotransmitter
     268117-PA
     Antagonist of neurosteroid potentiation and direct gating of GABAA
     2722Catestatin
     Inhibitor of nicotinic cholinergic-stimulated catecholamine secretion
     2701YM 90K hydrochloride
     Selective AMPA antagonist
     2723Anti-NR1
     Antibody recognising rat NR1 subunits
     2720Anti-NR2A
     Antibody recognising mouse NR2A subunits
     2687Pentylenetetrazole
     CNS stimulant
     2274PPPA
     Competitive NR2A antagonist
     2450NF 157
     Selective P2Y11/P2X1 antagonist
     2531Ganaxolone
     Potent, positive allosteric modulator of GABAA receptors
     2530PPDA
     Subtype-selective NR2C/NR2D antagonist
     2548NF 110
     Potent P2X3 antagonist
     2056Anti-phospho-NR2A (Ser1232)
     Antibody recognising rat NR2A subunits phosphorylated at Ser1232
     2049Anti-glutamate receptor δ1/2
     Antibody recognising rat glutamate receptor δ1 and δ2 subunits
     2062Anti-KA2
     Antibody recognising rat KA2 subunits
     2048Anti-GluR6/7
     Antibody recognising rat GluR6 and GluR7 subunits
     2047Anti-GluR5
     Antibody recognising rat GluR5 subunits
     2046Anti-GluR4
     Antibody recognising rat GluR4 subunits
     2041Anti-phospho-GluR1 (Ser831)
     Antibody recognising rat GluR1 subunits phosphorylated at Ser831
     2060Anti-NR3B
     Antibody recognising mouse NR3B subunits
     2059Anti-NR3A
     Antibody recognising rat NR3A subunits
     2054Anti-NR1, alternative CT
     Antibody recognising rat NR1 subunits with alternative C-terminus
    Sign-up for new product e-alerts
    Log In / Register

    User ID
    Password
    If you are not registered with us Create Account
    Home | About | Contact | Environment | Distributors | Glossary | Ordering | Security | Privacy | Terms & Conditions | Services | Site Map