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Category:
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Enzymes Phosphodiesterases
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Cat.No.
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Product Name
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2845 |
IBMX
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Price and Availability
Click here for full price details of
IBMX
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Chemical Name:
3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-d
ione |
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Biological Activity:
Phosphodiesterase inhibitor (IC50
values are 13, 18, 19, 32 and 50 μM for PDE4,
PDE3, PDE1, PDE5 and PDE2 respectively). Suppresses α-adrenoceptor-mediated
5-HT release from neuroendocrine epithelial cells (IC50 = 1.3 μM).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Freitag et al
(1998) Phosphodiesterase inhibitors suppress α2-adrenoceptor-mediated
5-hydroxytryptamine release from tracheae of newborn rabbits. Eur.J.Pharmacol. 354
67.
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View related products by Pharmacological Action
or by Research Area
Keywords: IBMX, Phosphodiesterases, PDE Inhibitor (non-selective), Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
| “Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..” Researcher, University of Aberdeen, UK |
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