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Category: 7TM ReceptorsarrowGABAB ReceptorsarrowAntagonists
Cat.No. Product Name
0245

2-Hydroxysaclofen  

Price and Availability

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2-Hydroxysaclofen
Chemical Name: (RS)-3-Amino-2-(4-chlorophenyl)-2-hydroxypropyl-sulfoni c acid

Biological Activity:

Selective antagonist at GABAB receptors.

Technical Data:

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M.Wt: 265.71
Formula: C9H12CINO4S
Storage: Store at RT
Solubility: Soluble to 5 mM in Water and to 100 mM in 1eq. NaOH
CAS No: [117354-64-0]

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    References:

    Kerr et al (1988) 2-Hydroxysaclofen: an improved antagonist at central and peripheral GABAB receptors. Neurosci.Lett. 92 92. Curtis et al (1988) Baclofen antagonism by 2-hydroxysaclofen in the cat spinal cord. Neurosci.Lett. 92 97.
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    Keywords: 2-Hydroxysaclofen, GABAB Receptors, Selective GABAB Antagonist, More Potent Than Saclofen (Cat. No. 0246), 2Hydroxysaclofen, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    GABA Receptors
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    Purity To Rely On
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