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Hydroxypropyl-b-cyclodextrin
Biological Activity:
The most widely used modified cyclodextrin, the lipophilic cavity
formed by 7 glucose units. Drug solubility in water is greatly enhanced by
complexing with HBC.
Pithaet al (1986) Hydroxypropyl-β-cyclodextrin: preparation and characterisation;
effects on solubilities of drugs. Int.J.Pharmacol. 29 73. Frijlink
(1991) The effects of cyclodextrins on the disposition of intravenously
injected drugs in the rat. Pharm.Res. 8 380.
“Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..”