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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNon-Selective Ionotropic Glutamate
Cat.No. Product Name
0291 N-(4-Hydroxyphenylpropanoyl) spermine trihydrochloride
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N-(4-Hydroxyphenylpropanoyl) spermine trihydrochloride
Chemical Name: N-(N-(4-Hydroxyphenylpropanoyl)-3-aminopropyl)-(N'-3-am inopropyl)-1,4-butanediamine trihydrochloride

Biological Activity:

Wasp toxin analogue. More potent than PhTX-343 at locust NMJ.

Technical Data:

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M.Wt: 459.89
Formula: C19H34N4O2.3HCl
Storage: Desiccate at -20°C
Solubility: Soluble to 50 mM in Water
CAS No: [130631-59-3]

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    References:

    Bycroft et al (1990) Invertebrate pharmacological assay of novel, potent glutamate antagonists: acylated spermines. Eur.J.Pharmacol. 183 470. Smith et al (1990) Mono-acylated spermines:  antagonists of glutamate receptors. Eur.J.Pharmacol. 183 472.
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    Keywords: N-(4-Hydroxyphenylpropanoyl) Spermine Trihydrochloride, Ligand-gated Ion Channels, Non-selective EAA Antagonist, N(4-Hydroxyphenylpropanoyl) Spermine Trihydrochloride, Tocris Bioscience
    Literature in this Area
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