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Category:
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7TM Receptors Dopamine ReceptorsD2-like ReceptorsD3-selective
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Cat.No.
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Product Name
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0706 |
7-Hydroxy-DPAT hydrobromide
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Price and Availability
Click here for full price details of
7-Hydroxy-DPAT hydrobromide
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Chemical Name:
(±)-7-Hydroxy-2-dipropylaminotetralin hydrobromide |
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Biological Activity:
D3 dopamine receptor agonist (Ki values are ~ 1, 10, 650 and ~ 5000 nM for D3,
D2, D4 and D1 receptors respectively).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Levesque et al (1992) Identification, characterization, and
localization of the dopamine D3 receptor in rat brain using [3H]-7-hydroxy-N,N-di-n-propyl-2-aminotetralin.
Proc.Natl.Acad.Sci.USA 89 8155. Daly and Waddington (1993)
Behavioural effects of the D3 dopamine receptor agonist 7-OH-DPAT in relation
to other D2-like agonists. Neuropharmacology 32 509. Seeman
and Van Tol (1994) Dopamine receptor pharmacology. TiPS 15
264. Levesque (1996) Aminotetralin
drugs and D3 receptor fuctions. Biochem.Pharmacol. 52 511.
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Keywords: 7-Hydroxy-DPAT Hydrobromide, Dopamine Receptors, Dopamine Agonist (D3 ³ D2 > D4), 7Hydroxy-DPAT Hydrobromide, Tocris Bioscience
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