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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNMDA SelectivearrowNMDA SitearrowAgonists
Cat.No. Product Name
0197 Homoquinolinic acid  
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Homoquinolinic acid

Biological Activity:

Potent NMDA receptor agonist; subtype selective.

Technical Data:

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M.Wt: 181.15
Formula: C8H7NO4
Storage: Store at RT
Solubility: Soluble to 100 mM in 1eq. NaOH
Purity: >99%
CAS No: [490-75-5]

Resources:

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    • Certificate of Analysis / MSDS:

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    References:

    Stone (1984) Excitant activity of methyl derivatives of quinolinic acid on rat cortical neurones. Br.J.Pharmacol. 81 175. Olverman et al (1988) Structure/activity relations of NMDA receptor ligands as studied by their inhibition of [3H]-D-2-amino-5-phosphonopentanoic acid binding in rat brain membranes. Neuroscience 26 17. Prado de Carvalho et al (1996) The endogenous agonist quinolinic acid and the non-endogenous homoquinolinic acid discriminate between NMDAR2 receptors subunits. Neurochem.Int. 28 445.

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    Keywords: Homoquinolinic Acid, Ligand-gated Ion Channels, Selective, Potent NMDA Agonist, Tocris Bioscience
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