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Category: EnzymesarrowKinasesarrowBroad Spectrum Protein Kinase Inhibitors
Cat.No. Product Name
0396

H-9 dihydrochloride  

Price and Availability

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H-9 dihydrochloride
Chemical Name: N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride

Biological Activity:

Protein kinase inhibitor. Inhibits PKA (Ki = 1.9 μM), PKG (Ki = 0.9 μM), CaMK II (Ki = 60 μM), PKC (Ki = 18 μM), casein kinase I (Ki = 110 μM) and casein kinase II (Ki > 300 μM).

Technical Data:

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M.Wt: 324.22
Formula: C11H13N3O2S.2HCl
Storage: Store at RT
Solubility: Soluble to 100 mM in Water
CAS No: [84468-17-7]

Resources:

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    • Certificate of Analysis / MSDS:

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    Product/Material Safety Data Sheet: View current batch

    References:

    Hidaka et al (1984) Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. Biochemistry 23 5036. Hidaka and Koybashi (1992) Pharmacology of protein kinase inhibitors. Ann.Rev.Pharmacol.Toxicol. 32 377.
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    Keywords: H-9 Dihydrochloride, Kinases, Protein Kinase Inhibitor, H9 Dihydrochloride, Tocris Bioscience
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