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Category: Cellular Processes and ComponentsarrowExtracellular Matrix and Adhesion MoleculesarrowAdhesion Molecules
Cat.No. Product Name
1805 Gly-Pro-Arg-Pro
Alternative name(s): Anti-polymerant peptide
GPRP
Price and Availability

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Gly-Pro-Arg-Pro

Biological Activity:

Inhibitor of fibrin polymerisation; binds to fibrinogen (Ki = 400 μM). Anticoagulant.

Technical Data:

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M.Wt: 425.49
Formula: C18H31N7O5
Storage: Desiccate at -20°C
CAS No: [67869-62-9]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Laudano and Doolittle (1978) Synthetic peptide derivatives that bind to fibrinogen and prevent the polymerization of fibrin monomers. Proc.Natl.Acad.Sci.USA 75 3085. Laudano and Doolittle (1980) Studies on synthetic peptides that bind to fibrinogen and prevent fibrin polymerization. Structural requirements, number of binding sites, and species differences. Biochemistry 19 1013. Hsieh et al (1981) Fibrin polymerization. 1. Alkylating peptide inhibitors of fibrin polymerization. J.Med.Chem. 24 322.
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    Keywords: Gly-Pro-Arg-Pro, Extracellular Matrix & Adhesion Molecules, Inhibits Fibrin Polymerisation, Anti-polymerant Peptide, GPRP, GlyPro-Arg-Pro, Tocris Bioscience

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