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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNMDA SelectivearrowNMDA SitearrowAgonists
Cat.No. Product Name
0218

L-Glutamic acid

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L-Glutamic acid
Chemical Name: (S)-1-Aminopropane-1,3-dicarboxylic acid

Biological Activity:

The predominant excitatory transmitter in the mammalian central nervous system. Acts at ionotropic and metabotropic glutamate receptors.

Technical Data:

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M.Wt: 147.13
Formula: C5H9NO4
Storage: Store at RT
Solubility: Soluble to 100 mM in 1eq. NaOH
CAS No: [56-86-0]

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    References:

    Watkins and Evans (1981) Excitatory amino acid transmitters. Ann.Rev.Pharmacol.Toxicol. 21 165. Monaghan et al (1989) The excitatory amino acid receptors: their classes, pharmacology and distinct properties in the function of the central nervous system. Ann.Rev.Pharmacol.Toxicol. 29 365.
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    Keywords: L-Glutamic Acid, Ligand-gated Ion Channels, Endogenous NMDA Agonist, LGlutamic Acid, Tocris Bioscience
    Literature in this Area
    Scientific Reviews
    The Ins & outs of Glutamate Transporter Pharmacology
    Download PDF
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
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