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Ghrelin (human)
Biological Activity:
Endogenous agonist peptide for the orphan growth
hormone secretagogue (GHS) receptor. Produced mainly by the stomach, it
stimulates release of growth hormone from the pituitary gland in vitro and in
vivo, and regulates feeding, growth and energy production.
Kojimaet al
(1999) Ghrelin is growth-hormone-releasing acylated peptide from stomach.
Nature 402 656. Tolleet al (2001) In vivo and in
vitro effects of ghrelin/motilin-related peptide on growth hormone secretion in
the rat. Neuroendocrinology 73 54. Inui (2001) Ghrelin: an
orexigenic and somatotrophic signal from the stomach. Nature Rev.Neurosci. 2
551.
