Fenretinide | Retinoic Acid Receptors | Synthetic Retinoid. Potent Anti-cancer Agent | 4-HPR

Category:

Nuclear Receptors

Retinoic Acid Receptors

Cat.No.

Product Name

1396

Fenretinide

Alternative name(s):

4-HPR

Fenretinide C26H33NO2 N-(4-Hydroxyphenyl)retinamide

Price and Availability

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Fenretinide

Chemical Name: N-(4-Hydroxyphenyl)retinamide

Biological Activity:

Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids.

Technical Data:

M.Wt:	391.55
Formula:	C₂₆H₃₃NO₂
Storage:	Store at -20°C
Solubility:	Soluble to 100 mM in Ethanol and to 100 mM in DMSO
CAS No:	[65646-68-6]

Resources:

Certificate of Analysis / MSDS:

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References:

Ulukaya and Wood (1999) Fenretinide and its relation to cancer. Cancer Treat.Rev. 25 229. Takahashi (2000) Antioxidant properties of N-(4-hydroxyphenyl)retinamide (fenretinide). Biol.Pharm.Bull. 23 222. Le Doze et al (2000) Pharmacokinetics of all-trans retinoic acid, 13-cis retinoic acid, and fenretinide in plasma and brain of rat. Drug Metab.Disp. 28 205.

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Keywords: Fenretinide, Retinoic Acid Receptors, Synthetic Retinoid. Potent Anti-cancer Agent, 4-HPR, Tocris Bioscience

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