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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGABAA and GABAC ReceptorsarrowBenzodiazepines
Cat.No. Product Name
0659 FGIN-1-43  
Price and Availability

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FGIN-1-43
Chemical Name: N,N-Dihexyl-2-(4-chlorophenyl)-5-chloroindole-3-acetami de

Biological Activity:

Most active of the 2-aryl-3-indoleacetamides; a new class of potent and specific ligands as probes for the mitochondial DBI receptor (peripheral benzodiazepine receptor).

Technical Data:

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M.Wt: 487.51
Formula: C28H36Cl2N2O
Storage: Store at RT
Solubility: Soluble to 50 mM in DMSO
CAS No: [145040-29-5]

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    • Certificate of Analysis / MSDS:

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    References:

    Romeo et al (1992) 2-Aryl-3-indoleacetamides (FGIN-1-43): a new class of potent and specific ligands for the mitochondrial DBI receptor (MDR). J.Pharmacol.Exp.Ther. 262 971. Kozikowski et al (1993) Chemistry, binding affinities, and behavioural properties of a new class of 'antineophobic' mitochondrial DBI receptor (mDRC) ligands. J.Med.Chem. 36 2908.
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    Keywords: FGIN-1-43, Ligand-gated Ion Channels, Potent, Specific Ligand For Mitochondrial DBI Receptor, Tocris Bioscience
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