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Category: 7TM ReceptorsarrowGlutamate (Metabotropic) ReceptorsarrowGroup I mGlu ReceptorsarrowAgonists
Cat.No. Product Name
1058 L-3'-F2CCG-I
Price and Availability

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L-3'-F2CCG-I

Other Information:

Sold with the permission of Nippon Chemiphar Co Ltd
Chemical Name: (2S,1'S,2'S)-2-(2'-Carboxy-3',3'-difluorocyclopropyl)gl ycine

Biological Activity:

Metabotropic glutamate receptor agonist, exhibits "priming" effect on the monosynaptic reflex.

Technical Data:

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M.Wt: 195.12
Formula: C6H7F2NO4
Storage: Desiccate at +4°C
Solubility: Soluble to 100 mM in Water

Resources:

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    References:

    Shinozaki et al (1996) Pharmacological activities of fluoride CCG derivatives: discovery of a novel agonist for metabotropic glutamate receptors. Soc.Neurosci.Abstr. 22 412.3. Saitoh et al (1998) Potentiation by DL-α-aminopimelate of a novel mGluR agonist (L-F2CCG-I) on the monosynaptic excitation in the rat spinal cord. Br.J.Pharmacol. 123 771. Ishida and Shinozaki (1999) Inhibition of uptake and release of a novel mGluR agonist (L-F2CCG-I) by anion transport blockers in the rat spinal cord. Neuropharmacology 38 1531.
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    Keywords: L-3-F2CCG-I, Glutamate (Metabotropic) Receptors, Potent Group I / Group II Agonist, L3-F2CCG-I, Tocris Bioscience

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