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Category:
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Cellular Processes and Components Other Signal TransductionProtein translocation/Exocytosis/Endocytosis
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Cat.No.
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Product Name
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1850 |
Exo1
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Price and Availability
Click here for full price details of
Exo1
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Chemical Name:
2-[(4-Fluorobenzoyl)amino]-benzoic acid methyl ester |
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Biological Activity:
Reversible inhibitor of vesicular trafficking between endoplasmic
reticulum and Golgi apparatus. Modifies Golgi ADP-ribosylation factor (ARF)1
GTPase activity and inhibits exocytosis (IC50 ~ 20 μM). Has similar, but not
identical, action to brefeldin A (Cat. No. 1231).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Feng et al (2003) Exo1: A new chemical inhibitor of the
exocytic pathway. Proc.Natl.Acad.Sci.USA 100 6469.
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View related products by Pharmacological Action
or by Research Area
Keywords: Exo1, Other Signal Transduction, Inhibits Golgi-ER Traffic; Blocks Exocytosis, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
| “Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..” Researcher, University of Aberdeen, UK |
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