Eticlopride | Dopamine Receptors | Selective D2 / D3 Antagonist | (-)-Eticlopride

Category:

7TM Receptors

Dopamine Receptors

D2-like Receptors

Antagonists

Cat.No.

Product Name

1847

Eticlopride hydrochloride

Alternative name(s):

(-)-Eticlopride

Price and Availability

Click here for full price details of
Eticlopride

Chemical Name: 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl ]-6-hydroxy-2-methoxy-benzamide hydrochloride

Biological Activity:

Selective dopamine D₂/D₃ receptor antagonist (K_i values are 0.50 and 0.16 nM respectively). Antipsychotic.

Technical Data:

M.Wt:	377.31
Formula:	C₁₇H₂₅ClN₂O₃.HCl
Storage:	Desiccate at RT
Solubility:	Soluble to 100 mM in Water
Purity:	>99%
CAS No:	[97612-24-3]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Hall et al (1985) Some in vitro receptor binding properties of [³H]eticlopride, a novel substituted benzamide, selective for dopamine-D₂ receptors in the rat brain. Eur.J.Pharmacol. 111 191. Giuliani and Ferrari (1997) Involvement of dopamine receptors in the antipsychotic profile of (-) eticlopride. Physiol.Behav. 61 563. Claytor et al (2006) The effects of eticlopride and the selective D₃-antagonist PNU 99194-A on food- and cocaine-maintained responding in rhesus monkeys. Pharmacol.Biochem.Behav. 83 456.

View related products by Pharmacological Action or by Research Area

Keywords: Eticlopride, Dopamine Receptors, Selective D2 / D3 Antagonist, (-)-Eticlopride, Tocris Bioscience

Literature in this Area

Scientific Reviews

Dopamine Receptors
Download PDF

Unique & Diverse Compound Libraries

Tocriscreen Collections : For pricing and compound information click here

Fully annotated small molecule libraries for HTS, HCS and
chemical biology applications.

1120 compounds
Pre-dissolved in DMSO

Tocriscreen Total (250 μL/well)
Tocriscreen Mini (50 μL/well)

New Products in this Area

	2735	PNU 96415E
	D₄ and 5-HT_2A antagonist; antipsychotic
	1519	Quinelorane hydrochloride
	D₂ and D₃ agonist
	2759	B-HT 920
	D₂ receptor agonist. Also α₂ agonist and 5-HT₃ antagonist
	2599	OSU 6162 hydrochloride
	Dopamine stabiliser
	2635	NGB 2904
	Potent and selective D₃ antagonist
	2664	Cabergoline
	Selective D₂-like agonist
	2536	Domperidone
	Peripheral D₂-like antagonist
	2547	6-Hydroxydopamine hydrochloride
	Selective catecholaminergic neurotoxin

for new product e-alerts

User ID
Password