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Category: 7TM ReceptorsarrowGlutamate (Metabotropic) ReceptorsarrowGroup I mGlu ReceptorsarrowAntagonists
Cat.No. Product Name
1009 E4CPG
Price and Availability

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E4CPG
Chemical Name: (RS)-a-Ethyl-4-carboxyphenylglycine

Biological Activity:

Novel group I/group II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG (Cat. No. 0336).

Technical Data:

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M.Wt: 223.23
Formula: C11H13NO4
Storage: Store at RT
Solubility: Soluble to 100 mM in 1.1eq. NaOH
Purity: >99%

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    References:

    Bedingfield et al (1995) Structure-activity relationships for a series of phenylglycine derivatives acting at metabotropic glutamate receptors (mGluRs). Br.J.Pharmacol. 116 3323. Sekiyama et al (1996) Structure-activity relationships of new agonists and antagonists of different metabotropic glutamate receptor subtypes. Br.J.Pharmacol. 117 1493.

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    Keywords: E4CPG, Glutamate (Metabotropic) Receptors, Group I / Group II MGlu Antagonist, Tocris Bioscience
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