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Category: EnzymesarrowKinasesarrowProtein Kinase C
Cat.No. Product Name
0749

Dihydrosphingosine  

Alternative name(s): Sphinganine
Price and Availability

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Dihydrosphingosine
Chemical Name: DL-erythro-1,3-Dihydroxy-2-aminooctadecane

Biological Activity:

Protein kinase C inhibitor.

Technical Data:

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M.Wt: 301.51
Formula: C18H39NO2
Storage: Desiccate at -20°C
Solubility: Soluble to 100 mM in DMSO
CAS No: [3102-56-5]

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    References:

    Yung et al (1993) Differential regulation of protein kinase C isoenzymes during sphinganine potentiation of retinoic acid-induced granulocytic differentiation in human leukemia HL-60 cells. Biochem.Biophys.Res.Comm. 196 1390. Yung et al (1994) Sphinganine potentiation of dimethyl sulfoxide-induced granulocyte differentiation, increase of alkaline phosphatase activity and decrease of protein kinase C activity in a human leukemia cell line (HL-60). Biochem.Biophys.Res.Comm. 199 888.
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    Keywords: Dihydrosphingosine, Kinases, Protein Kinase C Inhibitor, Sphinganine, Tocris Bioscience
    Literature in this Area
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    “I am grateful for your honesty and courtesy. The principles of Tocris are very different to that of your competitors who, in fact, have put our inhibitor on the market without any approval, exhibiting a pirate policy and a total absence of ethics..”
    Researcher, University of Pisa, Italy
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