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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGABAA and GABAC ReceptorsarrowGABAA ReceptorsarrowOther
Cat.No. Product Name
0505 Dihydroergotoxine mesylate  
Price and Availability

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Dihydroergotoxine mesylate

Biological Activity:

A complex of closely related alkaloid salts. Binds with high affinity to the GABAA receptor Cl- channel and has anticonvulsant and sedative activity. May also interact with central dopaminergic, serotonergic and adrenergic (α1) receptors. Inhibits prolactin.

Technical Data:

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Formula:  
Storage: Store at RT
Solubility: Soluble in Ethanol
CAS No: [8067-24-1]

Resources:

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    • Certificate of Analysis / MSDS:

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    Product/Material Safety Data Sheet: View current batch

    References:

    Tvrdeic and Pericic (1991) Dihydrogenated ergot compounds bind with high affinity to GABAA receptor-associated Cl- ionophore. Eur.J.Pharmacol. 202 109. Tvrdeic and Pericic (1992) Dihydroergotoxine modulation of the GABAA receptor-associated Cl- ionophore in mouse brain. Eur.J. Pharmacol. 221 139.
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    Keywords: Dihydroergotoxine Mesylate, Ligand-gated Ion Channels, Binds With High Affinity To GABAA Receptor Cl- Channel, Tocris Bioscience
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