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Category:
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7TM Receptors Adrenergic ReceptorsGeneral Alpha Receptors
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Cat.No.
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Product Name
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0475 |
Dihydroergotamine mesylate
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Price and Availability
Click here for full price details of
Dihydroergotamine mesylate
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Chemical Name:
9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)erg
otaman-3',6',18-trione mesylate |
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Biological Activity:
Partial α-adrenergic agonist.
Partial D2 dopaminergic receptor agonist. Competitive 5-HT
antagonist.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
de Boer et al (1991) Carotid vascular effects of ergotamine and
dihydroergotamine in the pig: no exclusive mediation via 5-HT1-like receptors. Br.J.Pharmacol. 104 183. Villalon
et al (1992) Effects of S9977 and dihydroergotamine in an animal
experimental model for migraine. Pharmacol.Res. 25 125. Doggrell
et al (1992) Further analysis of the inhibitory effects of
dihydroergotamine, cyproheptadine and ketanserin on the responses of the rat
aorta to 5-hydroxytryptamine. J.Aut.Pharmacol. 12 223. Lesage
et al (1998) Agonistic properties of alniditan, sumatriptan and
dihydroergotamine on human 5-HT1B and 5-HT1D receptors expressed in various mammalian
cell lines. Br.J.Pharmacol. 123 1655.
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View related products by Pharmacological Action
or by Research Area
Keywords: Dihydroergotamine Mesylate, Adrenergic Receptors, Partial A Agonist. Non Selective , Tocris Bioscience
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| “I am grateful for your honesty and courtesy. The principles of Tocris are very different to that of your competitors who, in fact, have put our inhibitor on the market without any approval, exhibiting a pirate policy and a total absence of ethics..” Researcher, University of Pisa, Italy |
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