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Category:
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Enzymes Synthases/SynthetasesOther Synthases/Synthetases
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Cat.No.
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Product Name
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0500 |
N1,N12-Diethylspermine tetrahydrochloride
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Price and Availability
Click here for full price details of
N1,N12-Diethylspermine tetrahydrochloride
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Biological Activity:
Powerful antineoplastic agent in cultured cells and animal
tumours. Inhibitor of polyamine synthases. Suppressor of mitochondrial DNA
synthesis.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Bergeron et al (1988) Synthetic polyamine analogues as antineoplastics.
J.Med.Chem. 31 1183. Vertino et al (1991) Selective
cellular depletion of mitochondrial DNA by the polyamine analog N1,N12-bis(ethyl)spermine
and its relationship to polyamine structure and function. Mol.Pharmacol. 39
487. Porter et al (1990) Combined regulation of arginine and
S-adenosylmethionine decarboxylases by spermine and the spermine analogue N1,N12-bis(ethyl)spermine.
Biochem.J. 268 207.
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or by Research Area
Keywords: N1,N12-Diethylspermine Tetrahydrochloride, Synthases / Synthetases, Polyamine Synthase Inhibitor, N1N12-Diethylspermine Tetrahydrochloride, Tocris Bioscience
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