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Category: Cellular Processes and ComponentsarrowSignal TransductionarrowNitric Oxide SignallingarrowOther Nitric Oxide
Cat.No. Product Name
0476 2,4-Diamino-6-hydroxypyrimidine  
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2,4-Diamino-6-hydroxypyrimidine

Biological Activity:

Inhibits the biosynthesis of tetrahydrobiopterin and thus suppresses the activity of NO synthase.

Technical Data:

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M.Wt: 126.12
Formula: C4H6N4O
Storage: Desiccate at +4°C
Solubility: Soluble in DMSO
Purity: >99%
CAS No: [56-06-4]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Werner-Felmayer et al (1993) Pteridine biosynthesis in human endothelial cells. Impact of NO-mediated formation of cyclic GMP. J.Biol.Chem. 268 1842. Moore and Handy (1997) Selective inhibitors of neuronal nitric oxide synthase - is no NOS really good NOS for the nervous system? TiPS 18 204.

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    Keywords: 2,4-Diamino-6-hydroxypyrimidine, Signal Transduction, Inhibits Biosynthesis Of Tetrahydrobiopterin & Thus NOS, 2,4Diamino-6-hydroxypyrimidine, Tocris Bioscience

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