Daidzein | Cell Cycle | Arrests Cell Cycle In G1 Phase

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Cat.No.	Product Name
1417	Daidzein

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Daidzein

Chemical Name: 7-Hydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Biological Activity:

Analogue of the phytoestrogen genistein (Cat. No. 1110). Blocks G1 phase cell cycle progression and is an agonist at estrogen receptors.

Technical Data:

M.Wt:	254.24
Formula:	C₁₅H₁₀O₄
Storage:	Desiccate at -20°C
Solubility:	Soluble to 100 mM in DMSO
Purity:	>99%
CAS No:	[486-66-8]

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References:

Jing et al (1993) Differentiation of promyelocytic leukemia cells HL-60 induced by daidzein in vitro and in vivo. Anticancer Res. 13 1049. Higashi and Ogawara (1994) Daidzein inhibits insulin- or insulin-like growth factor-1-mediated signaling in cell cycle progression of Swiss 3T3 cells. Biochim.Biophys.Acta 1221 29. Casanova et al (1999) Development effects of dietary phytoestrogens in Sprague Dawley rats and interactions of genistein and daidzein with rat estrogen receptors alpha and beta in vitro. Toxicol.Sci. 51 236.

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Keywords: Daidzein, Cell Cycle, Arrests Cell Cycle In G1 Phase, Tocris Bioscience

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