Tocris Bioscience
Welcome to Tocris

| Advanced Search
Home Products Technical Support Customer Support Literature Custom Synthesis
Category: 7TM ReceptorsarrowAdrenergic ReceptorsarrowAdrenergic-Related Compounds
Cat.No. Product Name
2958 DSP-4
Price and Availability

Click here for full price details of
DSP-4
Chemical Name: N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine hydrochloride

Biological Activity:

Adrenergic neurotoxin. Displays neurotoxic effects on both peripheral and central noradrenergic neurons.

Technical Data:

Click here for more information on batch specific data
M.Wt: 313.06
Formula: C11H15BrClN.HCl
Storage: Desiccate at RT
Solubility: Soluble to 100 mM in Water and to 100 mM in Ethanol
Purity: >99%
CAS No: [40616-75-9]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Jaim-Etcheverry and Zieher (1980) DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons of adult and developing rats. Brain Res. 188 513. Haidkind et al (2002) Denervation of the locus coeruleus projections by treatment with the selective neurotoxin DSP-4 [N(2-chloroethyl)-N-ethyl-2-bromobenzylamine] reduces dopamine release potential in the nucleus accumbens shell in conscious rats. Neurosci.Letts. 332 79. Kawamura et al (2005) Short and long term analysis of heart rate variations in spontaneous hypertensive rats: effect of DSP-4 administration. Biomed.Pharmacother. 59 S203.
    View related products by Pharmacological Action or by Research Area

    Keywords: DSP-4, Adrenergic Receptors, Adrenergic Neurotoxin, DSP4, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Adrenoceptor Pharmacology
    Download PDF
    We always order directly from Tocris since the service is so impeccable. I can only praise the Tocris customer service team who are ready to assist us in every way, without delay. Customer support I receive from other suppliers pales in comparison.”
    Researcher, Chemical Research Center, Hungary
    New Products in this Area

     2964Doxazosin mesylate
     α1-adrenoceptor antagonist
     1051Zinterol hydrochloride
     Selective β2 agonist
     2958DSP-4
     Adrenergic neurotoxin
     2838(R)-(-)-Phenylephrine hydrochloride
     α1-adrenoceptor agonist
     2806Alprenolol hydrochloride
     β antagonist
     2398SNAP 5089
     Subtype selective α1A-adrenoceptor antagonist
     2638ST 91
     α2 agonist, putative α2C agonist
     2685Carvedilol
     β-adrenoceptor and α1-adrenoceptor antagonist
     2658Bucindolol
     β1- and β2-adrenoceptor antagonist
     2666JP 1302 dihydrochloride
     Potent and selective α2C antagonist
     1811Modafinil
     Psychostimulant
    Sign-up for new product e-alerts
    Log In / Register

    User ID
    Password
    If you are not registered with us Create Account