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Category:
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7TM Receptors Adrenergic Receptors Adrenergic-Related Compounds
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Cat.No.
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Product Name
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2958 |
DSP-4
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Price and Availability
Click here for full price details of
DSP-4
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Chemical Name:
N-(2-Chloroethyl)-N-ethyl-2-bromobenzylamine
hydrochloride |
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Biological Activity:
Adrenergic neurotoxin. Displays
neurotoxic effects on both peripheral and central noradrenergic neurons.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Jaim-Etcheverry and Zieher
(1980) DSP-4: a novel compound with neurotoxic effects on noradrenergic neurons
of adult and developing rats. Brain Res. 188 513. Haidkind
et al (2002) Denervation of the locus coeruleus projections by treatment
with the selective neurotoxin DSP-4 [N(2-chloroethyl)-N-ethyl-2-bromobenzylamine]
reduces dopamine release potential in the nucleus accumbens shell in conscious
rats. Neurosci.Letts. 332 79. Kawamura et al (2005)
Short and long term analysis of heart rate variations in spontaneous
hypertensive rats: effect of DSP-4 administration. Biomed.Pharmacother. 59
S203.
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or by Research Area
Keywords: DSP-4, Adrenergic Receptors, Adrenergic Neurotoxin, DSP4, Tocris Bioscience
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