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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGABAA and GABAC ReceptorsarrowBenzodiazepines
Cat.No. Product Name
3083 DMCM hydrochloride
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DMCM hydrochloride
Chemical Name: 4-Ethyl-6,7-dimethoxy-9H-pyrido[3,4-b]indole-3-carboxyl ic acid methyl ester hydrochloride

Biological Activity:

Benzodiazepine inverse agonist that displays anxiogenic and potent convulsant activity.

Technical Data:

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M.Wt: 350.8
Formula: C17H18N2O4.HCl
Storage: Desiccate at RT
Purity: >98%
CAS No: [82499-00-1]

Resources:

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    • Certificate of Analysis / MSDS:

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    Product/Material Safety Data Sheet: View current batch

    References:

    Petersen (1983) DMCM: a potent convusive benzodiazepine receptor ligand. Eur.J.Pharmacol. 94 117. Sieve et al (2001) Pain and negative affect: evidence the inverse benzodiazepine agonist DMCM inhibits pain and learning in rats. Psychopharmacol. 153 180. Conto et al (2005) Behavioral differences between subgroups of rats with high and low threshold to clonic convulsions induced by DMCM, a benzodiazepine inverse agonist. Pharmacol.Biochem.Behav. 82 417.
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    Keywords: DMCM Hydrochloride, Ligand-gated Ion Channels, Benzodiazepine Inverse Agonist, Tocris Bioscience
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