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Category:
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7TM Receptors Melatonin (MT) Receptors
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Cat.No.
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Product Name
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1218 |
DH 97
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Price and Availability
Click here for full price details of
DH 97
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Chemical Name:
N-Pentanoyl-2-benzyltryptamine |
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Biological Activity:
A relatively potent MT2
melatonin receptor antagonist (pKi value = 8.03), displaying 89- and
229-fold selectivity over the MT1 and mel1C subtypes.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Teh and Sugden (1998) Comparison of the relationships of melatonin
receptor agonists and antagonists; lengthening the N-acyl side chain has
differing effects on potency on Xenopus melanophores.
Naunyn-Schmied.Arch.Pharmacol. 358 522. Ting et al
(1999) Molecular and pharmacological evidence for MT1 melatonin
receptor subtype in the tail artery of juvenile Wistar rats. Br.J.Pharmacol. 127
987.
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or by Research Area
Keywords: DH 97, Melatonin (MT) Receptors, MT2 Receptor Antagonist, DH97, Tocris Bioscience
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