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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlutamate (Ionotropic) ReceptorsarrowNon-Selective Ionotropic Glutamate
Cat.No. Product Name
1395 (R)-3,4-DCPG
Price and Availability

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(R)-3,4-DCPG
Chemical Name: (R)-3,4-Dicarboxyphenylglycine

Biological Activity:

AMPA receptor antagonist with weak activity at NMDA receptors and little activity at kainate receptors.

Technical Data:

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M.Wt: 239.18
Formula: C­10H9NO6
Storage: Desiccate at RT
Solubility: Soluble to 100 mM in Water
Purity: >98%

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    References:

    Thomas et al (1997) Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur.J.Pharmacol. 338 111. Moldrich et al (2001) Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology 40 732.
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    Keywords: (R)-3,4-DCPG, Ligand-gated Ion Channels, AMPA Antagonist / Weak NMDA Antagonist, 3,4DCPG, Tocris Bioscience
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