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Category: Ion ChannelsarrowChloride Channels
Cat.No. Product Name
1422 DCEBIO
Price and Availability

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DCEBIO
Chemical Name: 5,6-Dichloro-1-ethyl-1,3-dihydro-2H-benzimidazol-2-one

Biological Activity:

Stimulates Cl- secretion via activation of hIK1 K+ channels and the activation of an apical Cl- conductance. More potent than its analogue 1-EBIO (Cat. No. 1041).

Technical Data:

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M.Wt: 231.08
Formula: C9H8Cl2N2O
Storage: Store at RT
Solubility: Soluble to 100 mM in DMSO and to 100 mM in Ethanol
Purity: >99%
CAS No: [60563-36-2]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
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    Product/Material Safety Data Sheet: View current batch
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    References:

    Singh et al (2001) Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease. J.Pharmacol.Exp.Ther. 296 600.
    View related products by Pharmacological Action or by Research Area

    Keywords: DCEBIO, Chloride Channels, Activates Cl- Conductance & HIK1 K+ Channels, Tocris Bioscience

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