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Category: 7TM ReceptorsarrowAcetylcholine (Muscarinic) ReceptorsarrowAntagonists
Cat.No. Product Name
0482 4-DAMP  
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4-DAMP
Chemical Name: 1,1-Dimethyl-4-diphenylacetoxypiperidinium iodide

Biological Activity:

Antagonist at the M3 cholinergic receptor. [3H]-4-DAMP selectively labels M1 and M3 receptors.

Technical Data:

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M.Wt: 451.33
Formula: C21H26INO2 
Storage: Store at RT
Solubility: Soluble to 25 mM in DMSO
Purity: >99%
CAS No: [1952-15-4]

Resources:

  • Certificate of Analysis / MSDS:

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    Product/Material Safety Data Sheet: View current batch
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    References:

    Barlow and Shepherd (1986) A further search for selective antagonists at M2- muscarinic receptors. Br.J.Pharmacol. 89 837. Michel et al (1989) Direct labelling of rat M3-muscarinic receptors by [3H]4-DAMP. Eur.J.Pharmacol. 166 459.
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    Keywords: 4-DAMP, Acetylcholine (Muscarinic) Receptors, Muscarinic M3 Antagonist , 4DAMP, Tocris Bioscience

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