W-Conotoxin GVIA | Calcium Channels | Ca2+ Channel Blocker (N-type) | Omega-Conotoxin GVIA

Category:

Cat.No.	Product Name
1085	w-Conotoxin GVIA

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w-Conotoxin GVIA

Biological Activity:

Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels.

Technical Data:

M.Wt:	3037
Formula:	C₁₂₀H₁₈₈N₃₈O₄₃S₆
Storage:	Desiccate at -20°C
CAS No:	[106375-28-4]

Resources:

Certificate of Analysis / MSDS:

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References:

Tsien et al (1988) Multiple types of neuronal calcium channels and their selective modulation. TiNS 11 431. Casali et al (1997) Different effects of reducing agents on ω-conotoxin GVIA inhibition of [³H]-acetylcholine release from rat cortical slices and guinea-pig myenteric plexus. Br.J.Pharmacol. 120 88. Wright and Angus (1997) Prolonged cardiovascular effects of the N-type Ca²⁺ channel antagonist ω-conotoxin GVIA in conscious rabbits. J.Cardiovasc.Pharmacol. 30 392.

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Keywords: W-Conotoxin GVIA, Calcium Channels, Ca2+ Channel Blocker (N-type), Omega-Conotoxin GVIA, Tocris Bioscience

Literature in this Area

Scientific Reviews

Mechanisms for Manipulating Intracellular Calcium Buffering
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