Conessine | Histamine Receptors | Potent & Selective H3 Receptor Antagonist

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Cat.No.	Product Name
2409	Conessine

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Conessine

Chemical Name: N,N-Dimethyl-con-5-enin-3-amine

Biological Activity:

Potent and selective histamine H₃ receptor antagonist. A steroidal alkaloid that displays in vitro antiplasmodial activity (IC₅₀= 1.04 μM).

Technical Data:

M.Wt:	356.59
Formula:	C₂₄H₄₀N₂
Storage:	Store at RT
Solubility:	Soluble to 50 mM in Ethanol and to 50 mM in DMSO
CAS No:	[546-06-5]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Zirihi et al (2005) Isolation, characterization and antiplasmodial activity of steroidal alkaloids from Funtumia elastica (Preuss) Stapf. Bioorg.Med.Chem.Lett. 15 2637. Witte et al (2005) Discovery of a novel natural product of unique chemical structure as a potent and selective histamine H₃ receptor (H₃R) antagonist. Soc.Neurosci.Abstr. 491.19.

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Keywords: Conessine, Histamine Receptors, Potent & Selective H3 Receptor Antagonist, Tocris Bioscience

Literature in this Area

Scientific Reviews

Histamine Receptors
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