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Category: Cellular Processes and ComponentsarrowCytoskeleton and Motor ProteinsarrowMicrotubules
Cat.No. Product Name
1364 Colchicine
Price and Availability

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Colchicine
Chemical Name: (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxob enzo[a]heptalen-7-yl)acetamide

Biological Activity:

Plant-derived alkaloid that binds to tubulin and depolymerizes microtubules.

Technical Data:

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M.Wt: 399.44
Formula: C22H25NO6
Storage: Store at RT
Solubility: Soluble to 100 mM in Ethanol and to 100 mM in Water
Purity: >99%
CAS No: [64-86-8]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Hastie (1991) Interactions of colchicine with tubulin. Pharmacol.Ther. 51 377. Burns (1992) Analysis of the colchicine-binding site of β-tubulin. FEBS Lett. 297 205. Bai et al (1996) Identification of cysteine 354 of β-tubulin as part of the binding site for the A ring of colchicine. J.Biol.Chem. 271 12639. 
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    Keywords: Colchicine, Cytoskeleton & Motor Proteins, Inhibitor Of Tubulin, Tocris Bioscience

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