Clemastine Fumarate | Histamine Receptors | H1 Antagonist

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Cat.No.	Product Name
1453	Clemastine fumarate

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Clemastine fumarate

Chemical Name: (2R)-2-[2-[(1R)-1-(4-Chlorophenylethoxy]ethyl]-1-methyl -2-pyrrolidine fumarate

Biological Activity:

H₁-receptor antagonist. Clinically-used antihistamine.

Technical Data:

M.Wt:	459.97
Formula:	C₂₁H₂₆ClNO.C₄H₄O₄
Storage:	Store at RT
Solubility:	Soluble to 5 mM in Water
Purity:	>98%
CAS No:	[14976-57-9]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Hartmann et al (1981) Modulation of histamine-induced bronchoconstriction with inhaled, oral, and intravenous clemastine in normal and asthmatic subjects. Thorax 36 737. Dorsch et al (1982) Histamine1-histamine2 antagonism: effect of combined clemastine and cimetidine pretreatment on allergen and histamine-induced reactions of the guinea pig lung in vivo and in vitro. Agents Actions 12 113. Nair and Schwartz (1983) Effect of histamine and histamine antagonists on natural and antibody-dependent cellular cytotoxicity of human lymphocytes in vitro. Cell.Immunol. 81 45.

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Keywords: Clemastine Fumarate, Histamine Receptors, H1 Antagonist, Tocris Bioscience

Literature in this Area

Scientific Reviews

Histamine Receptors
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